Week 7 2022
Significance and Practical Applications for Tumor Phenotyping (IHC/MSI) in Hereditary Cancer Risk Assessment
- Determine which cases of CRC have defective mismatch repair
- Screen for Lynch syndrome among newly diagnosed CRC & EC patients
- Discuss OSU clinical experience doing IHC on all newly diagnosed CRC & EC patients
- Review EGAPP recommendations
Clinical Management of Hereditary Gastrointestinal Cancers
- Recognize standard of care screening guidelines for individuals with increased risks for gastrointestinal cancers associated with hereditary cancer syndromes, including Lynch, Familial Adenomatous Polyposis, Peutz-Jeghers and Juvenile Polyposis syndromes)
- Identify established and emerging surgical and chemopreventive risk management recommendations and options for hereditary gastrointestinal cancers
- Understand the spectrum and limits of established and emerging screening and risk management for individuals with hereditary risk for diffuse gastric and pancreatic cancers
Heather Hampel, MS, CGC
Associate Director, Division of Clinical Cancer Genomics
City of Hope
Heather Hampel completed her Bachelor of Science degree in Molecular Genetics at the Ohio State University in 1993. She attained her Master’s degree in Human Genetics from Sarah Lawrence College in 1995. She received certification from the American Board of Genetic Counseling in 1996. She worked as a cancer genetic counselor at Memorial Sloan-Kettering Cancer Center from 1995-1997 and at The Ohio State University from 1997-2021. She is now at City of Hope National Medical Center where she is a Professor in the Department of Medical Oncology & Therapeutics Research and Associate Director of the Division of Clinical Cancer Genomics. Her research areas of interest include Lynch syndrome and universal screening for Lynch syndrome. She has over 90 publications; including first author publications in the New England Journal of Medicine, Cancer Research, and the Journal of Clinical Oncology. Heather is a former member of the Board of Directors of the National Society of Genetic Counselors (Region IV Representative in 2003-4) and of the American Board of Genetic Counseling (2007-2011) where she served as President in 2009 and 2010. She received the Region IV Leadership Award from NSGC in 2006. She was on the Steering Committee of the National Colorectal Cancer Roundtable from 2016-2020. She was on the Council for the Collaborative Group of the Americas on Inherited Gastrointestinal Cancers from 2015-2018 and served as president from 2017-2018. She was Secretary/Treasurer Elect of NSGC in 2021 and will be Secretary/Treasurer in 2022.
Patrick Lynch, MD
Professor, Department of Gastroenterology, Hepatology, & Nutrition
The University of Texas MD Anderson Cancer Center
Dr. Patrick Lynch is a gastroenterologist and scientist with specific expertise in cancer risk for mismatch repair gene mutation carriers. He is a Professor of Medicine in the Department of Gastroenterology, Hepatology and Nutrition at UT-MD Anderson Cancer Center in Houston, Texas. Dr. Lynch received his Law degree and degree in Medicine from Creighton University. His internship and residency were at the University of Arkansas for Medical Sciences. He completed his Fellowship in Gastroenterology at Baylor College of Medicine in Houston, Texas. Dr. Lynch provides surveillance for patients and families with hereditary colorectal cancers, and is actively involved in the counseling and management of these patients and families. He has led or collaborated on multiple NIH- and industry-funded studies in hereditary colorectal cancers, including basic science, clinical, chemoprevention and behavioral studies. He is a member of Council for and past President of the International Society for Gastrointestinal Hereditary Tumors (INSIGHT) and is past President of the Collaborative Group of the Americas on Inherited Colorectal Cancer. He was recently awarded a grant under the UTMDACC “Moonshot” program for further development of a web-based registry for familial cancer families.
Lauren Gima, MS, CGC
City of Hope
Lauren Gima, MS, CGC is a board-certified, licensed genetic counselor at City of Hope in Duarte, CA where she specializes in clinical cancer genomics. She earned her MS degree in Genetic Counseling from Northwestern University and BS degree in Human Biology from University of California San Diego. Her primary clinical responsibilities include providing cancer genetic counseling services for City of Hope’s patient population. She is a clinical rotation supervisor for students of the Keck Graduate Institute (KGI) Genetic Counseling program, the University of California Irvine Genetic Counseling program, and the University of California Los Angeles Genetic Counseling program. She also serves as a community mentor for the KGI Genetic Counseling program, providing ongoing support and guidance for new genetic counseling students. Lauren is a member of the National Society of Genetic Counselors, the Collaborative Group of the Americas on Inherited Gastrointestinal Cancers, the Southern California Genetic Counselors, and the Minority Genetics Professionals Network.
Deanna Erwin, MS, CGC
Genetic Counselor, Interim Supervisor
Deanna Erwin MS, CGC, is a licensed, board-certified genetic counselor specializing in cancer genetics. She has a Master’s degree in Genetic Counseling from the University of Michigan and a Bachelor’s degree in Biology and Psychology from the University of Massachusetts, Amherst.
Her primary clinical focus is providing risk assessment and genetic counseling services to individuals concerned about hereditary cancer risks. Ms. Erwin joined the City of Hope Division of Clinical Cancer Genomics in 2019, and previously worked as a genetic counselor at the Baylor College of Medicine Adult Genetics Clinic in Houston, TX. She is an active member of the National Society of Genetic Counselors (NSGC) and is currently serving as Vice-Chair of the Access and Service Delivery Committee. As part of her role in NSGC, she has contributed to multiple resources designed to increase provider efficiency and access to genetic counselors.