If you are seeing this page, then you are not signed or have not yet enrolled in the City of Hope/VA Cancer Genomics in Practice course. To begin your enrollment, return to the homepage by clicking the button below, then sign in and click the yellow "ENROLL" button at the top right of the page.

HOMEPAGE

If you need assistance, contact us at CGEP@coh.org.

image

Instruction
3 Learning Modules &
1 Elective Module

image

Time
2.00 Hours

image

Tasks
3 Quizzes


➤ Bundle 01 Learner Notification

➤ Bundles 01-10 Learner Notification for ABIM MOC (pending)

Basic Genetics Primer, Part 1

  • Describe the basic principles of gene structure, function, and regulation
  • Appreciate the nature and consequences of major types of gene mutations

Basic Genetics Primer, Part 2

  • Outline the principles of Mendelian inheritance.
  • Identify the features of incomplete penetrance and variable expressivity.
  • Recognize how genetic mechanisms such as de novo mutations, mosaicism and imprinting can affect the pattern of cancer in a family.

The Basic Science of Cancer Genetics

  • Distinguish the differences between somatic and germline mutations.
  • Describe the roles of oncogenes and tumor suppressor genes in signal transduction and cell cycle control.
  • Review the mechanisms of DNA damage

Lauren Gima, MS, CGC

Senior Genetic Counselor

City of Hope

LAUREN GIMA, MS, CGC is a board-certified, licensed genetic counselor at City of Hope in Duarte, CA, where she specializes in clinical cancer genomics. She earned her MS degree in Genetic Counseling from Northwestern University and BS degree in Human Biology from University of California San Diego. Her primary clinical responsibilities include providing cancer genetic counseling services for City of Hope’s patient population and her primary research interest is in hereditary GI cancer syndromes. Ms. Gima is a faculty member of the City of Hope Intensive Course and Clinical Cancer Genomics Community of Practice, and an adjunct faculty member for the Keck Graduate Institute Genetic Counseling and Genomic Data Analytics masters’ programs. She serves as a clinical rotation supervisor for genetic counseling students and as a mentor for the KGI Genetic Counseling program, providing ongoing support and guidance for new genetic counseling students. Lauren is a member of the National Society of Genetic Counselors, the Collaborative Group of the Americas on Inherited Gastrointestinal Cancers, the Southern California Genetic Counselors, the Minority Genetics Professionals Network, and the Alliance for Genomic Justice.

Susan Shehayeb, MS, CGC

Senior Genetic Counselor

City of Hope

SUSAN SHEHAYEB, MS, CGC,  is a licensed board-certified genetic counselor specializing in cancer genetics. She has a Master’s of Science degree in genetic counseling from University of California Irvine. Previous to completing her master’s degree, Ms. Shehayeb earned her bachelor’s degree in molecular, cell and developmental biology from University of California Los Angeles. Ms. Shehayeb joined the City of Hope Division of Clinical Cancer Genomics in 2017, having previously undergone clinical training at City of Hope. She is fluent in Arabic and is in the process of achieving fluency in Spanish.

Ms. Shehayeb's clinical role has centered on widening patient access to genetic counseling and testing throughout the City of Hope clinical network and on genetics representation and expertise in the setting of gynecologic oncology. She co-leads the curriculum development for educational initiatives within the City of Hope Clinical Division of Cancer Genomics. Her research work and special interests focus on hereditary breast and ovarian cancers, hereditary genodermatoses, precision medicine in hereditary cancer care, and Justice, Equity, Diversity, and Inclusion (JEDI) in cancer genetics training. She is a member of the National Society of Genetic Counselors and the Southern California Genetic Counselors.

Rachelle Manookian, MS, CGC

Genetic Counselor

Children's Hospital of Los Angeles

RACHELLE MANOOKIAN, MS, CGC is a licensed and board-certified cancer genetic counselor specializing in pediatric oncology at Children’s Hospital Los Angeles (CHLA). She was previously with the Division of Clinical Cancer Genomics at City of Hope, and before that, a general genetic counselor at the West VA Medical Center. She brings her growing expertise in medical education to her role as an adjunct faculty member for the Keck Graduate Institute Genetic Counseling and Genomic Data Analytics master’s programs. She serves as a faculty mentor, graduate capstone supervisor, and rotation supervisor for current genetic counseling students. She is actively engaged in the Fanconi anemia community and has been a volunteer at Fanconi Anemia Family Week since 2016, and she is a two-time nominee of the Heart of Genetic Counseling Award from the National Society of Genetic Counselors.

 

Kathryn Reyes, MS, CGC

Genetic Counselor

City of Hope

Kathryn Reyes, MS, CGC is a board-certified genetic counselor specializing in cancer genetics at City of Hope. She earned her Master of Science degree in Human Genetics and Genetic Counseling from Stanford University and her Bachelor of Science degree in Biological Sciences from the University of California, Irvine. Prior to joining City of Hope in 2022, Kathryn previously worked as a cancer genetic counselor at Cedars-Sinai Medical Center in Los Angeles. In addition to her role providing patient care, Kathryn has interests in genetic counseling research and education. Her research investigates the psychological effects of undergoing multi-gene panel testing for hereditary cancer susceptibility. She also serves on the Research, Quality and Outcomes Committee of the National Society of Genetic Counselors. Kathryn gives lectures on cancer genetics topics to local Southern California genetic counseling programs and is currently one of the Education Co-Chairs of the Southern California Genetic Counselors group.

 

Key:

Complete
Failed
Available
Locked
Basic Genetics Primer, Part 1
Open to view video.  |  47 minutes
Open to view video.  |  47 minutes Describe the basic principles of gene structure, function, and regulation Appreciate the nature and consequences of major types of gene mutations
Quiz 01A
4 Questions  |  Unlimited attempts  |  10/12 points to pass
4 Questions  |  Unlimited attempts  |  10/12 points to pass Quiz for Basic Genetics Primer, Part 1
Basic Genetics Primer, Part 2
Open to view video.  |  58 minutes
Open to view video.  |  58 minutes Outline the principles of Mendelian inheritance. Identify the features of incomplete penetrance and variable expressivity. Recognize how genetic mechanisms such as de novo mutations, mosaicism and imprinting can affect the pattern of cancer in a family.
Review Quiz 01B
2 Questions  |  Unlimited attempts  |  6/7 points to pass
2 Questions  |  Unlimited attempts  |  6/7 points to pass Quiz for Basic Genetics Primer, Part 2
The Basic Science of Cancer Genetics
Open to view video.  |  24 minutes
Open to view video.  |  24 minutes Distinguish the differences between somatic and germline mutations. Describe the roles of oncogenes and tumor suppressor genes in signal transduction and cell cycle control. Review the mechanisms of DNA damage
Quiz 01C
6 Questions  |  Unlimited attempts  |  8/9 points to pass
6 Questions  |  Unlimited attempts  |  8/9 points to pass Quiz for The Basic Science of Cancer Genetics
Learning Evaluation
Bundle 01 Evaluation
10 Questions
10 Questions Please respond to the statements in this evaluation as they relate to your experiences with this review bundle. This survey will take less than 3 minutes to complete. This survey should be completed AFTER you have completed all required items in this module.
Bundle 01 Credits
Complete the form at the AMEDCO link to earn your credit from completing this bundle.
Bundle 01 Completion Code
After completing all 10 bundles and the webinar feedback forms, use the provided code to verify your completion of this bundle.
Elective Modules
Micro Learning: NCCN Guidelines Overview (ELECTIVE)
Open to view video.  |  18 minutes
Open to view video.  |  18 minutes