Week 3 2022

COLIN PRITCHARD, MD, PhD, is a Professor of Laboratory Medicine and Pathology at the University of Washington and Program Director for Cancer Precision Diagnostics for the Brotman Baty Institute for Precision Medicine. He also serves as the Co-Director of the Genetics and Solid Tumors Laboratory that services the Fred Hutchinson Cancer Center. The Pritchard laboratory focuses on oncology molecular diagnostics, particularly the source and utility of cell-free nucleic acid biomarkers in blood, and the development of innovative molecular diagnostics for the identification of DNA repair gene mutations that can guide therapeutic decision-making. His clinical work focuses on applications of next-generation sequencing gene panels for cancer risk assessment and precision treatment. He has led the development and implementation of the ColoSeq™ Lynch and Polyposis Syndrome Panel and the UW-OncoPlex™ Cancer Gene Panel in current clinical use for cancer patients and their families. He is a longstanding distinguished faculty member of the City of Hope Clinical Cancer Genomics Community of Practice. In 2021 Dr. Pritchard was awarded the C2 Catalyst for Precision Medicine Award from Scientific American.

Danielle Castillo, BS, is a Senior Research Associate in the Department of Clinical Cancer Genetics Molecular Laboratory at the City of Hope, where she assists Mr. Herzog in the maintenance of the Breast Cancer Registry, Hispanic Mutation Project, LiFTUP Project and other research endeavors. After spending a good part of her senior year working on water conservation at Stellenbosch University in Cape Town, South Africa Mrs. Castillo graduated with a bachelor’s degree in biology from Whittier College in 2008 Mrs. Castillo worked as a biologist for Irvine Scientific before coming to the City of Hope in early 2009.

BITA NEHORAY, MS, CGC, is a licensed board-certified genetic counselor specializing in cancer genetics. She received her Master’s degree in Human Genetics and Genetic Counseling from Stanford University. Ms. Nehoray joined the City of Hope Division of Clinical Cancer Genomics in 2012. As a Senior Genetic Counselor she provides cancer genetics services for patients and families suspected to have a hereditary predisposition to cancer, with a focus in Li-Fraumeni syndrome and Clonal Hematopoiesis of Indeterminate Potential. Current research projects include understanding cancer risk, penetrance, prevalence, and clinical outcomes for individuals with TP53 pathogenic variants as part of the LiFT UP study, evaluating the spectrum of germline variants in Israeli breast cancer patients, and assessing community-based provider experiences with polygenic risk scores in genetic cancer risk assessment. She also serves on the genetic counseling advisory committee for the Li-Fraumeni Syndrome Association and is a member of the ClinGen TP53 Variant Curation Expert Panel. She is fluent in Spanish and Farsi and is committed to advancing the provision of cancer genetics services to medically underserved and culturally diverse populations. She is faculty for the City of Hope Intensive Course in Genetic Cancer Risk Assessment. She is an active member of the National Society of Genetic Counselors, Southern California Genetic Counselors, and the American Society of Human Genetics.